Lung Function in Patients Receiving Busulphan

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Lung function in patients receiving busulphan.

An attempt was made to achieve earlier detection of busulphan lung (fibrosing alveolitis) and to determine its incidence by means of serial studies during life, including measurement of the gas transfer factor. Twenty-three patients were investigated over an average period of nearly two years of busulphan treatment. One case of busulphan lung was detected and subsequently confirmed at necropsy,...

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A child receiving busulphan treatment for adult-type chronic myeloid leukaemia responded well for four years before the onset of complications leading to "busulphan lung'. Pulmonary function tests (PFT) were useful in monitoring the development of this condition and we recommended regular PFT for patient receiving busulphan treatment.

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ژورنال

عنوان ژورنال: BMJ

سال: 1970

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.4.5734.530